What are the potential benefits of GHK-Cu for skin?

GHK-Cu has been studied for its potential role in supporting skin firmness, elasticity, texture, collagen-related pathways, and the appearance of fine lines and wrinkles. Individual results may vary.

GHK-Cu cream vs. injections: What's the difference?

Topical GHK-Cu cream is applied directly to the skin, while injectable GHK-Cu is administered systemically. FDA currently treats the two routes differently under its 503A compounding framework. Non-injectable GHK-Cu is included in FDA's Category 1 interim policy, while injectable GHK-Cu is excluded from that Category 1 treatment.

How long does GHK-Cu cream take to work?

Visible changes from topical GHK-Cu, when they occur, generally develop gradually with consistent use. Response can vary depending on the formulation, frequency of use, skin condition, and other products used at the same time.

Does GHK-Cu help with wrinkles and collagen?

GHK-Cu has been studied for its role in collagen-related pathways, skin firmness, elasticity, and the appearance of fine lines and wrinkles. Human clinical evidence remains limited, and individual results may vary.

Prescription Only Medication

GHK-Cu 1%

Q: What is GHK-Cu cream?

GHK-Cu cream is a topical formulation containing glycyl-L-histidyl-L-lysine copper, a copper-binding peptide studied for its role in collagen and elastin pathways, extracellular-matrix support, and overall skin quality.

Topical Cream

From $96/mo

GHK-Cu is a copper-binding peptide studied for its role in collagen and extracellular matrix support. This clinician-prescribed 1% topical cream is designed for daily use as part of a personalized approach to skin firmness, texture, and visible signs of aging.

Supports collagen & elastin pathways

Helps improve skin firmness & elasticity

Supports smoother-looking texture & fine lines

Designed for daily topical use

See If You Qualify

Prescription products require an online consultation with a healthcare provider who will determine whether treatment is appropriate.

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HIPAA-secure

HSA & FSA Eligible

U.S. - Licensed clinicians

Free shipping

HIPAA-secure

HSA & FSA Eligible

U.S. - Licensed clinicians

Free shipping

Mith

Healthy skin is simply a matter of skincare.

Reality

Skin health is influenced by biology, hormones, aging, nutrition, sleep, stress, genetics, and your environment.

what is GHK-Cu

Learn more about GHK-Cu

Always talk to a doctor or medical provider for guidance tailored to your health needs.

What to Expect

Changes in skin quality can develop over time

GHK-Cu has been studied for its role in processes involved in collagen, elastin, and extracellular-matrix support. Visible changes, when they occur, tend to develop gradually with consistent use.

Changes in skin quality over 12 weeks

Line graph showing percent change from baseline over 12 weeks for Collagen & Elastin, Wrinkle reduction, and Texture & Firmness. Collagen & Elastin increases steeply to about 70%, Wrinkle reduction rises moderately to around 25%, and Texture & Firmness increases slowly to about 15%.

Human studies of topical GHK-Cu have evaluated changes over approximately 8–12 weeks. Individual results vary.

Woman with wavy brown hair wearing a light purple top and robe, smiling gently while applying cream to her cheek with her hand indoors.

AFTER 4 WEEKS

Early changes

Some people may begin to notice improvements in skin texture, hydration, or overall feel with consistent use.

AFTER 8 WEEKS

Noticeable changes

Changes in texture, firmness, and overall skin quality may become more noticeable over time.

AFTER 12 WEEKS

Visible progress

Continued use may support further improvements in the appearance of texture, firmness, fine lines, and overall skin quality.

Published studies of topical GHK-Cu have generally evaluated outcomes over several weeks to approximately 12 weeks. Individual results vary.

the benefits

How GHK-Cu supports skin biology

These potential benefits reflect biological mechanisms and findings from published research. Human clinical evidence remains limited, and individual results may vary.

See If You Qualify

Smiling woman with clear, glowing skin and brown hair in a messy bun, resting her hand on her cheek in a softly lit, cozy indoor setting with plants and wooden furniture in the background.

Licensed Pharmacy

Peptide Based

Personalized Care

Silicon Free

Paraben Free

Prescription Only

HOW IT WORKS

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