What are the benefits of GHK-Cu + Estriol Cream?

The formula is designed to support several aspects of changing skin, including dryness, reduced firmness, uneven tone, texture, elasticity, and visible signs of aging. Each ingredient works through a different pathway.

How does estriol help menopausal skin?

Estriol interacts with estrogen receptors in skin tissue and has been studied for its potential to support hydration, elasticity, firmness, and skin thickness in women experiencing hormone-related skin changes.

Why are niacinamide and hyaluronic acid included?

Niacinamide supports the skin barrier and helps improve the appearance of uneven tone, texture, and fine lines. Hyaluronic acid helps attract and retain moisture, supporting hydration, comfort, and a smoother-looking appearance.

Who may be a good candidate for GHK-Cu + Estriol Cream?

The cream may be considered for women experiencing skin changes associated with perimenopause, menopause, or declining estrogen levels, including dryness, reduced firmness, uneven tone, or thinning-looking skin. A licensed provider determines whether treatment is appropriate.

How long does GHK-Cu + Estriol Cream take to work?

Visible changes, when they occur, generally develop gradually with consistent use. Timing varies depending on skin condition, frequency of use, formulation, and other skincare products being used.

Can GHK-Cu + Estriol Cream be used with tretinoin or other skincare actives?

It may be used alongside other skincare treatments, but combining multiple active ingredients can increase the chance of irritation or sensitivity. A healthcare provider can help determine how to incorporate the cream into an existing skincare routine.

Prescription Only Medication

GHK-Cu + Estriol Complex

Q: What is GHK-Cu + Estriol Cream?

GHK-Cu + Estriol Cream is a compounded topical prescription cream combining GHK-Cu, estriol, niacinamide, and hyaluronic acid to support hydration, firmness, skin structure, tone, texture, and overall skin quality.

Q: What does GHK-Cu do for the skin?

GHK-Cu is a copper-binding peptide studied for its interaction with fibroblast activity, collagen-related pathways, and extracellular-matrix processes involved in skin structure and renewal.

With Niacinamide + Hyaluronic Acid · 30 g

From $139/mo

A clinician-prescribed topical formula combining GHK-Cu, estriol, niacinamide, and hyaluronic acid to support skin affected by hormonal changes — including dryness, loss of firmness, uneven tone, and visible signs of aging.

Supports hydration & skin comfort

Helps maintain firmness & elasticity

Supports collagen & skin structure

Promotes smoother, more even-looking skin

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Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.

Image for illustration purposes only.

HIPAA-secure

HSA & FSA Eligible

U.S. - Licensed clinicians

Free shipping

HIPAA-secure

HSA & FSA Eligible

U.S. - Licensed clinicians

Free shipping

Mith

Healthy skin is simply a matter of skincare.

Reality

Skin health is influenced by biology, hormones, aging, nutrition, sleep, stress, genetics, and your environment.

what it is

Learn more about Estriol / GHK-Cu

Always talk to a doctor or medical provider for guidance tailored to your health needs.

WHAT'S IN YOUR FORMULA

Four ingredients.
One complete skin approach.

Each ingredient plays a different role — supporting hormonal skin changes, skin structure, and barrier health from complementary pathways.

Estriol 0.3%

A topical estrogen studied for its role in supporting skin hydration, elasticity, thickness, and other estrogen-responsive skin functions.

GHK-Cu 0.2%

A copper-binding peptide studied for its interaction with fibroblast activity, collagen-related pathways, and extracellular-matrix processes involved in skin structure.

Niacinamide 3%

A form of vitamin B3 that supports the skin barrier and helps improve the appearance of uneven tone, texture, and visible signs of aging.

Hyaluronic Acid

A moisture-binding ingredient that helps support hydration, skin comfort, and a smoother-looking appearance.

the benefits

The science behind the formula of GHK-Cu + Estriol Complex

Note: These potential benefits reflect the biological properties of GHK-Cu and findings from published research. Individual results may vary.

See If You Qualify

Smiling woman with clear, glowing skin and brown hair in a messy bun, resting her hand on her cheek in a softly lit, cozy indoor setting with plants and wooden furniture in the background.

Licensed Pharmacy

Peptide Based

Personalized Care

Silicon Free

Paraben Free

Prescription Only

HOW IT WORKS

Your care in 3 easy steps

BeMediq connects you with licensed medical providers for personalized women's health care. From your first online visit to treatment delivered to your door, everything is designed to fit your life.